About Bethyl Laboratories | Fortis Life Sciences

Bethyl Laboratories began as a family-owned company in Montgomery, Texas, earning a reputation for rigorous antibody validation that set the standard for the industry. Since joining Fortis Life Sciences in 2020, Bethyl has continued those same validation practices while expanding its Farm-to-Bench™ capabilities and providing customers with access to the specialized expertise of six complementary life science companies.

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Bethyl By the Numbers

Bethyl Laboratories laboratory
Laboratory
0sq ft

45,000 square feet of lab space: western blotting, in-house custom-column antibody purification, cell sorting, phage display, and custom spatial biology/IHC panel design

0°C / 0°C / 0°C

Cold storage at 4°C, -20°C, -80°C, and liquid nitrogen

Bethyl Laboratories animal facilities
Animal Facilities
0pastures
more than 0 acres

15 pastures across more than 100 acres

0ponds

8 man-made hydration and enrichment ponds with connected plumbing

Automatic solar-powered feeders

and fresh waters in every pasture and barn

0systems

11 veterinary plasmapheresis collection systems

On-site backup generator

and temperature-controlled animal facilities

0sq ft

50,000 square feet of climate-controlled rabbit housing

Six-Pillar Validation

Identifying the intended target is only the first requirement. An antibody also has to show high sensitivity with minimal cross-reactivity. Bethyl tests specificity against paired antibodies raised to distinct epitopes on the same protein, rather than trusting a single antibody's result.

Specificity has to hold in immunoprecipitation or Western blot before an antibody moves on to testing in immunohistochemistry, immunocytochemistry, ChIP, or proximity ligation assay.

Bethyl serves to advance science by developing highly-qualified antibodies, including many to emerging and underserved protein targets.

See our Six-Pillar Validation methodology

Custom Antibody Development

Bethyl built custom antibody programs for decades, complete packages spanning peptide synthesis through affinity purification against an antigen-specific immunosorbent.

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Membrane proteins, ion channels, and other structurally difficult epitopes often call for a different discovery method, VHH single-domain antibodies.

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Antibody Manufacturing You Can Trust

Bethyl manufactures and validates every antibody in-house at its Montgomery, Texas facility, spanning veterinary care, development, production, and validation in one integrated system.

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Montgomery now operates as one of six Fortis manufacturing and R&D sites.

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USDA

Registration & Assurance

As a USDA-registered research facility, Bethyl adheres to the Animal Welfare Act in the care of the animals behind every antibody it produces.

USDA Class R Research Facility Registration #74-R-0044
PHS/NIH/OLAW Animal Welfare #A3991-01
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